Biotechnology PhD Training Program

UVa

 

Bacterial Motility/Infectivity/Metabolism, Biodefense

  How do interactions between bacterial and host membrane proteins mediate bacterial infection? What are the mechanisms of action of bacterial toxins?  How do viruses gain entry?  What is the role of bacterial membrane channels in antibiotic resistance?  How do brain and retinal cells regulate CD8+ T cell migration post Toxoplasma gondii infection?  How do commensal bacteria influence the immune system in cancer?

    How can systems biology be applied to the understanding of pathogen-host signaling interactions and to bacterial metabolomes? 

    How can red blood cell-based immune complex clearance be applied to the eradication of pathogens from the circulation?

    Can a vaccine be developed to biodefense category B agent Entamoeba histolytica that promotes 50 million illnesses and 100,000 deaths annually? Can new bactericidal agents be derived from multipurpose proteins? 

    How can sensors be developed for biological warfare detection?

How can bacterial chemotaxis and microalgae be applied to bioremediation of hazardous wastes?

Faculty engaged in this research

Columbus

Ewald

Gahlmann  

Harris Tajie

Laurie

Papin

Petri [video]

Rutkowski

Tamm